منابع مشابه
Cardiac resynchronization therapy acutely improves diastolic function.
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Myocardial diastolic dysfunction is the relaxation abnormality of ventricles that limits the diastolic filling and generally precedes diastolic heart failure. Diastolic dysfunction is a common finding in diabetes. Diabetic patients receive hyperbaric oxygen (HBO) therapy for non-healing lower extremity ulcers, and exposure to HBO therapy is known to influence cardiovascular functions. This stud...
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Experimental studies demonstrated that mineralocorticoid antagonists prevent or reverse myocardial fibrosis. Therefore, we tested the hypothesis that the aldosterone antagonist canrenone can improve left ventricular diastolic function in essential hypertension. Using digitized M-mode echocardiography and 24-hour blood pressure monitoring (ABPM), we realized a prospective, randomized, controlled...
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BACKGROUND Incomplete relaxation of the left ventricle (LV) affects LV filling, but the subsequent effect on LV systolic function remains unclear. We attempted to improve relaxation by applying oscillatory mechanical perturbation during diastole (diastolic vibration) and examined the extent to which systolic function improved. METHODS AND RESULTS Using 10 open-chest canine preparations, pacin...
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Diastolic dysfunction can lead to heart failure with preserved ejection fraction, for which there is no effective therapeutic. Ranolazine has been reported to reduce diastolic dysfunction, but the specific mechanisms of action are unclear. The effect of ranolazine on diastolic function was examined in spontaneously hypertensive rats (SHRs), where left ventricular relaxation is impaired and stif...
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ژورنال
عنوان ژورنال: Clinical Cardiology
سال: 2005
ISSN: 0160-9289,1932-8737
DOI: 10.1002/clc.4960281008